Neural network activation during a stop-signal task discriminates cocaine-dependent from non-drug-abusing men
نویسندگان
چکیده
منابع مشابه
Neural network activation during a stop-signal task discriminates cocaine-dependent from non-drug-abusing men.
Cocaine dependence is defined by a loss of inhibitory control over drug-use behaviors, mirrored by measurable impairments in laboratory tasks of inhibitory control. The current study tested the hypothesis that deficits in multiple subprocesses of behavioral control are associated with reliable neural-processing alterations that define cocaine addiction. While undergoing functional magnetic reso...
متن کاملMicrosaccade production during saccade cancelation in a stop-signal task
We obtained behavioral data to evaluate two alternative hypotheses about the neural mechanisms of gaze control. The "fixation" hypothesis states that neurons in rostral superior colliculus (SC) enforce fixation of gaze. The "microsaccade" hypothesis states that neurons in rostral SC encode microsaccades rather than fixation per se. Previously reported neuronal activity in monkey SC during the s...
متن کاملLower activation in the right frontoparietal network during a counting Stroop task in a cocaine-dependent group.
Dysregulation in cognitive control networks may mediate core characteristics of drug addiction. Cocaine dependence has been particularly associated with low activation in the frontoparietal regions during conditions requiring decision making and cognitive control. This functional magnetic resonance imaging (fMRI) study aimed to examine differential brain-related activation to cocaine addiction ...
متن کاملCocaine disposition in meconium from newborns of cocaine-abusing mothers and urine of adult drug users.
The analysis of meconium for cocaine and metabolites has proved to be a reliable method for the detection of fetal cocaine exposure. Better sensitivity and a larger gestational window of detection have been demonstrated for meconium testing as compared with neonatal urine testing. Cocaine and cocaine metabolites, including benzoylecgonine, ecgonine methyl ester, cocaethylene, norcocaine, benzoy...
متن کاملPretreatment brain activation during stroop task is associated with outcomes in cocaine-dependent patients.
BACKGROUND Cognitive behavioral and related therapies for cocaine dependence may exert their effects, in part, by enhancing cognitive control over drug use behavior. No prior studies have systematically examined the neural correlates of cognitive control as related to treatment outcomes for cocaine dependence. METHODS Twenty treatment-seeking cocaine-dependent individuals performed a Stroop c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Addiction Biology
سال: 2012
ISSN: 1355-6215
DOI: 10.1111/adb.12011